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Prostate Cancer Trials

Statuses

Locations

TYPE

Prostate

STATUS

In Follow-up

LOCATION

NSW | VIC | QLD | SA | WA

PROTOCOL #

ANZUP 2101

ANZadapt

Phase II randomised controlled trial of patient-specific adaptive versus continuous Abiraterone or eNZalutamide in metastatic castration-resistant prostate cancer
Trial assessing whether adaptive (pause–restart) hormone treatment compared to continuous hormone treatment improves outcomes for people with advanced…

TYPE

Prostate

STATUS

Recruiting

LOCATION

NSW | VIC | QLD | WA | NZ

PROTOCOL #

ANZUP2205

DARO-LIPID

Randomised Phase 2 study of sphingosine kinase inhibitor (opaganib) in addition to darolutamide in people with poor prognostic metastatic castration …
Trial assessing whether adding a new treatment (opaganib) to standard therapy improves outcomes for a selected group of people with advanced, treatmen…

TYPE

Prostate

STATUS

In Follow-up

LOCATION

NSW | VIC | QLD | SA | TAS | WA | NZ | Ireland | Canada | USA

PROTOCOL #

ANZUP 1801

DASL-HiCaP

Darolutamide Augments Standard Therapy for Localised Very High-Risk Cancer of the Prostate
Trial assessing whether adding darolutamide to standard treatment improves outcomes for people with high-risk prostate cancer that has not spread bey…

TYPE

Prostate

STATUS

In Follow-up

LOCATION

NSW | VIC | QLD | SA | WA

PROTOCOL #

ANZUP 1901

ENZA-p

A randomised phase II trial using PSMA as a therapeutic agent and prognostic indicator in people with metastatic castration-resistant prostate cancer treated with enzalutamide.
Trial assessing whether adding a targeted radiation treatment (LuPSMA) to enzalutamide improves outcomes, and how PSMA PET/CT can help monitor disease…

TYPE

Prostate

STATUS

In Follow-up

LOCATION

NSW | VIC | QLD | NT | SA | TAS | WA | NZ | UK | Ireland | Canada | USA

PROTOCOL #

ANZUP 1304

ENZAMET

Enzalutamide in first line androgen deprivation therapy for metastatic prostate cancer: a randomised phase III trial
Trial assessing whether adding enzalutamide to standard therapy improves survival and quality of life as a first-line treatment for people with advanc…

TYPE

Prostate

STATUS

In Follow-up

LOCATION

NSW | VIC | QLD | SA | TAS | WA | NZ | UK | Ireland | Belgium | USA | Spain | Austria | Slovenia

PROTOCOL #

ANZUP 1303

ENZARAD

Enzalutamide in androgen deprivation therapy with radiation therapy for high risk, clinically localised, prostate cancer: a randomised phase III trial
Trial assessing whether adding enzalutamide to standard hormone therapy and radiation improves survival and quality of life for people with high-risk …

TYPE

Prostate

STATUS

In Follow-up

LOCATION

NSW | VIC | SA | WA

PROTOCOL #

ANZUP 2001

EVOLUTION

Phase II Study of Radionuclide 177Lu-PSMA Therapy versus 177Lu-PSMA in Combination with Ipilimumab and Nivolumab for people with Metastatic Castration Resistant Prostate Cancer
Trial assessing whether adding immunotherapy (ipilimumab and nivolumab) to a targeted radiation treatment (LuPSMA) improves outcomes for people with a…

TYPE

Prostate

STATUS

Recruiting

LOCATION

NSW | VIC | QLD

PROTOCOL #

ANZUP2102

GenI-AIRSPACE

Evaluating the effect of genomically informed treatment decision-making on long-term oncological outcomes for individuals diagnosed with intermediate …
Trial testing whether genomic test results can help guide decisions between active surveillance and treatment for people with favourable intermediate-…

TYPE

Prostate

STATUS

In Follow-up

LOCATION

NSW | VIC | QLD | SA | WA

PROTOCOL #

HREC/16/PMCC/130

proPSMA

A prospective randomised multi-centre study of the impact of Ga-68 PSMA-PET/CT imaging for staging high risk prostate cancer prior to curative-intent surgery or radiotherapy
Trial evaluating whether PSMA PET/CT scans can better detect cancer spread that may not be seen on standard scans and improve treatment decisions for …

TYPE

Prostate

STATUS

Recruiting

LOCATION

NSW | VIC | QLD | ACT | SA

PROTOCOL #

ANZUP 2201

WOMBAT

Working Out M0 Bipolar Androgen Therapy (WOMBAT)
Trial assessing whether cycles of testosterone treatment every 56 days, alongside standard hormone therapy, can help control prostate cancer for longe…

TYPE

Prostate

STATUS

In Follow-up

LOCATION

NSW | VIC | QLD | SA | WA

PROTOCOL #

18/047

#UpFrontPSMA

A Randomised Phase 2 Study of Sequential 177Lu-PSMA617 and Docetaxel Versus Docetaxel in Metastatic Hormone-Naive Prostate Cancer
Trial assessing whether adding a targeted radiation treatment (LuPSMA) before chemotherapy improves outcomes for people with advanced prostate cancer …

TYPE

Prostate

STATUS

In Follow-up

LOCATION

NSW | VIC | QLD | SA | WA | NZ

PROTOCOL #

TROG 18.01

NINJA

Novel Integration of new prostate radiation therapy schedules with adjuvant androgen deprivation
Trial assessing whether shorter, more targeted radiation schedules improve outcomes for people with intermediate- or high-risk prostate cancer that ha…