GUIDE

Current Clinical Trials

Prostate — Closed

The purpose of this study is to see if a prostate cancer marker in the blood (mGSTP1) can be used to guide chemotherapy treatment. Based on the level of this blood marker, some people may be able to have breaks in treatment rather than having chemotherapy continuously which is the current standard of care. This study will tell us if having these treatment breaks guided by mGSTP1 can improve how people feel during treatment while still treating the prostate cancer effectively.

If you think this trial might be right for you, please ask your doctor.

TRIAL TITLE

A phase II trial of biomarker-driven intermittent docetaxel in metastatic castration-resistant prostate cancer (mCRPC)

CANCER TYPE

Prostate

TRIAL STATUS

Closed

PROTOCOL NUMBER

ANZUP 1903

CO-ORDINATING CENTRE

ANZUP

STUDY CHAIR

Dr Kate Mahon

PATIENT POPULATION

The target population is men with mCRPC receiving docetaxel chemotherapy, with a detectable mGSTP1 at baseline (80% of all men commencing docetaxel for mCRPC)

RECRUITMENT TARGET

28 patients

ACKNOWLEDGEMENT

GUIDE is an investigator-initiated study sponsored and led by ANZUP. The study is funded by ANZUP Discretionary Funding Initiative, ANZUP Below the Belt Research Fund and Chris O’Brien Lifehouse Philanthropic Fund.