Published Research & Presentations

ANZUP Journal Articles 2019


Ian D. Davis, M.B., B.S., Ph.D., Andrew J. Martin, Ph.D., Martin R. Stockler, M.B., B.S., Stephen Begbie, M.B., B.S., Kim N. Chi, M.D., Simon Chowdhury, M.B., B.S., Ph.D., Xanthi Coskinas, M.Med.Sc., Mark Frydenberg, M.B., B.S., Wendy E. Hague, M.B., B.S., Ph.D., Lisa G. Horvath, M.B., B.S., Ph.D., Anthony M. Joshua, M.B., B.S., Ph.D., Nicola J. Lawrence, M.B., Ch.B., Gavin Marx, M.B., B.S., John McCaffrey, M.B., B.Ch., Ray McDermott, M.D., Ph.D., Margaret McJannett, R.N., Scott A. North, M.D., Francis Parnis, M.B., B.S., Wendy Parulekar, M.D., David W. Pook, M.B., B.S., M.D., M. Neil Reaume, M.D., Shahneen K. Sandhu, M.B., B.S., Alvin Tan, M.B., Ch.B., T. Hsiang Tan, M.B., B.S., Alastair Thomson, B.M., Emily Tu, Ph.D., Francisco Vera-Badillo, M.D., Scott G. Williams, M.B., B.S., M.D., Sonia Yip, Ph.D., Alison Y. Zhang, M.B., B.S., Robert R. Zielinski, M.B., B.S., and Christopher J. Sweeney, M.B., B.S. for the ENZAMET Trial Investigators and the Australian and New Zealand Urogenital and Prostate Cancer Trials Group*. Enzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer. NEJM, 2 June 2019.

Chiong E, Murphy DG, Akaza H, Buchan NC, Chung BH, Kanesvaran R, Khochikar M, Letran J, Lojanapiwat B, Ng CF, Ong T, Pu YS, Saad M, Schubach K, Türkeri L, Umbas R, Le Chuyen V, Williams S, Ye DW; ANZUP Cancer Trials Group, Davis ID. 
Management of patients with advanced prostate cancer in the Asia Pacific region: ‘real-world’ consideration of results from the Advanced Prostate Cancer Consensus Conference (APCCC) 2017. BJU Int. 2019;123(1):22-34. doi: 10.1111/bju.14489. BJU, January 2019.

Michael S. Hofman, Louise Emmett, John Violet, Alison Zhang, Nicky J. Lawrence, Martin Stockler, Roslyn J. Francis, Amir Iravani, Scott Williams, Arun Azad, Andrew Martin, Margaret McJannett, ANZUP TheraP team, Ian D. Davis. A randomised phase 2 trial of 177Lu-PSMA-617 theranostic versus cabazitaxel in progressive metastatic castration resistant prostate cancer: (ANZUP 1603)BJUI, submitted March 2019.

ANZUP Conference Presentations 2019


Christopher Sweeney, MMBS. 
Overall survival (OS) results of a phase III randomized trial of standard-of-care therapy with or without enzalutamide for metastatic hormone-sensitive prostate cancer (mHSPC): ENZAMET (ANZUP 1304), an ANZUP-led international cooperative group trial. ASCO Plenary presentation, 2 June 2019.


An international ra
ndomised phase 3 trial of accelerated versus standard BEP chemotherapy for adult and paediatric male and female patients with intermediate and poor-risk metastatic germ cell tumours: P3BEP (ANZUP 1302)ASCO GU, 14-16 February 2019.


TheraP: A randomized phase II trial of [177Lu]-PSMA-617 theranostic versus cabazitaxel in progressive metastatic castration-resistant prostate cancer. 
ASCO GU, 14 - 16 February 2019.

Dr Simeon Ngweso – Villas Marshall Prize Winner, 
Penile cancer in Western Australia: “Discrepancies in registry Coding for 
Penile cancer” and “The significance of demographic location in survival outcomes". USANZ ASM 2019.



ANZUP Journal Articles 2018


What survival benefits are needed to make Adjuvant Sorafenib worthwhile after resection of intermediate – or high-risk renal cell carcinoma? Clinical investigators’ preferences in the SORCE Trial. Kidney Cancer 2 (2018) 123–131. doi: 10.3233/KCA-180038. 16 July, 2018

P3BEP (ANZUP 1302): An international randomised phase III trial of accelerated versus standard BEP chemotherapy for adult and paediatric male and female patients with intermediate and poor-risk metastatic germ cell tumors (GCTs). Alison Yan Zhang, Guy C. Toner, Nicola Jane Lawrence, Martin R. Stockler, Andrew James Martin, Kate Ford, Amanda Gwendolyn Stevanovic, David Wyld, Euan Thomas Walpole, Simon Troon, Fritha J. Hanning, Girish Mallesara, Andrew James Weickhardt, Alison Jane Birtle, Ian D. Davis, Peter S. Grimison. Journal of Clinical Oncology.

Williams S. GDPR – not just an EU regulation? Lancet Oncol. 2018;19(10):e508. doi: 10.1016/S1470- 2045(18)30696-X. Lancet Oncology, October 2018.

Alison Yan Zhang, Guy C. Toner, Nicola Jane Lawrence, Martin R. Stockler, Andrew James Martin, Kate Ford, Amanda Gwendolyn Stevanovic, David Wyld, Euan Thomas Walpole, Simon Troon, Fritha J. Hanning, Girish Mallesara, Andrew James Weickhardt, Alison Jane Birtle, Ian D. Davis, Peter S. Grimison. An international randomized phase III trial of accelerated versus standard BEP chemotherapy for adult and paediatric male and female patients with intermediate and poor-risk metastatic germ cell tumors (GCTs). Journal of Clinical Oncology.

Michael Hofman, Louise Emmett, John A Violet, Nicola Jane Lawrence, Scott Williams, Martin R. Stockler, Roslyn J Francis, Amir Iravani, Alison Yan Zhang, Andrew James Martin, Arun Azad, Sonia Yip, Ailsa Langford, Margaret Mary McJannett, Ian D. Davis. A randomized phase II trial of [177Lu]- PSMA-617 theranostic versus cabazitaxel in progressive metastatic castration resistant prostate cancer. Journal of Clinical Oncology.

ANZUP Conference Presentations 2018


Randomised phase 3 trial of enzlautamide in androgen deprivation therapy (ADT) with radiation therapy for high risk, clinically localised prostate cancer: ENZARAD (ANZUP 1303).
American Society of Clinical Oncology – Genitourinary Cancers, San Francisco, February 2018.

Nayar N, Lawrence N, Stockler MR, Martin A, Yip S, Wong N, Yeung A, Friedlander M, Mazhar D, Pashankar F, Quinn DI, McDermott R, Walker R, Winstanley M, Hanning FJ, Weickhardt A, Stevanovic A, Davis ID, Toner GC, Grimison PS. An international randomised phase 3 trial of accelerated versus standard BEP chemotherapy for adult and paediatric male and female patients with intermediate and poor risk metastatic germ cell tumours: P3BEP (ANZUP 1302) American Society of Clinical Oncology – Genitourinary Symposium; 8–10 February 2018.

Srikala S Sridhar et al. Abstract #219679 CCTG BL12: Randomized phase II trial comparing nab-paclitaxel (Nab-P) to paclitaxel (P) in patients (pts) with advanced urothelial cancer progressing on or after a platinum containing regimen. 2018 American Society of Clinical Oncology (ASCO) Annual Meeting, McCormick Place, Chicago, IL, USA. 1-5 June 2018.

M. Stockler, et al. The ANZUP Phase 3 Accelerated BEP trial: A randomised phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumours. ASCO, Chicago, USA. 1-5 June, 2018.

Crossing the paediatric and adult hospital divide: An international randomised phase 3 trial of accelerated versus standard BEP chemotherapy for adult and paediatric male and female patients with intermediate and poor-risk metastatic germ cell tumours3rd AYA congress, 4-6 December, 2018

ANZUP Journal Articles 2017


Chambers SK, Occhipinti S, Foley E, Clutton S, Legg M, Berry M, Stockler MR, Frydenberg M, Gardiner RA, Lepore SJ, Davis ID, Smith DP. Mindfulness-based cognitive therapy in advanced prostate cancer: A randomized controlled trial. Journal of Clinical Oncology 2017; 35(3): 291-297.

Hayne D, Stockler M, McCombie SP, Lawrence N, Martin A, Sengupta S. The BCG+ Mitomycin trial for high risk non-muscle-invasive bladder cancer: Progress report and lessons learned. Brit J Urol Int 2017.

Heiniger, L. E., Smith, A. B., Olver, I., Grimison, P., Klein, B., Wootten, A., Butow, P. N. (2017). e-TC: Development and pilot testing of a web-based
intervention to reduce anxiety and depression in survivors of testicular cancer.
Eur J Cancer Care (Engl), 26(6). doi:10.1111/ecc.12698.

ANZUP Conference Presentations 2017


Lawrence N J, Martin A, Davis I D, Troon S, Sengupta S, Hovey E, Coskinas X, Kaplan R, Ritchie A W S, Meade A, Eisen T, Blinman P, Stockler M R. Predicted benefits of adjuvant sorafenib after nephrectomy for renal cell carcinoma (RCC) in SORCE: an international, placebo-controlled, randomised phase 3 trial. Poster presentation at European Society for Medical Oncology (ESMO) 2017: 8–12 September 2017, Madrid, Spain.

Randomised phase 3 trial of enzalutamide in androgen deprivation therapy with radiation therapy for clinically localised high risk or node-positive prostate cancer: the ENZARAD Trial (ANZUP 1303). American Society of Clinical Oncology, Chicago, June 2017.

Grimison P, Lawrence N, Stockler M, Martin A, Yip S, Wong N, Yeung A, Friedlander M, Mazhar D, Pashankar F, Quinn D, Walker R, Winstanley M, Hanning F,
Weickhardt A, Stevanovic A, Davis I, Toner G. P3 BEP (ANZUP 1302): An international randomised phase 3 trial of accelerated versus standard BEP chemotherapy for adult and paediatric male and female patients with intermediate and poor-risk metastatic germ cell tumours (GCTs). American Society of Clinical Oncology; 2–6 June 2017; Chicago, Illinois.

Nayar N, Lawrence N, Stockler M, Martin A, Yip S, Wong N, Yeung A, Friedlander M, Mazhar D, Pashankar F, Quinn D, Walker R, Winstanley M, Hanning F,
Weickhardt A, Stevanovic A, Davis I, Toner G, Grimison P. P3 BEP (ANZUP 1302): An international randomised phase 3 trial of accelerated versus standard BEP chemotherapy for adult and paediatric male and female patients with intermediate and poor-risk metastatic germ cell tumours (GCTs). Clinical Oncology Society of Australia; 13–15 November 2017; Sydney.

ANZUP Journal Articles 2016


Smith AB, Butow P, Olver I, Luckett T, Grimison P, Toner GC, Stockler MR, Hovey E, Stubbs J, Turner S, Hruby G, Gurney H, Alam M, Cox K, King MT. The prevalence, severity and correlation of psychological distress and impaired healthrelated quality of life following treatment for testicular cancer: a survivorship study. Journal of Cancer Survivorship: Research and Practice 2016; 10(2): 223-233.

Ussher JM, Perz J, Kellett A, Chambers S, Latini D, Davis ID, Rose D, Dowsett GW, Williams S. Health-related quality of life, psychological distress and sexual changes following prostate cancer: a comparison of gay and bisexual men with heterosexual men. Journal of Sexual Medicine 2016; 13(3): 425-434. 

Rose, D., Ussher, J., & Perz, J. (2016). Let’s talk about gay sex: Gay and bisexual men’s sexual communication with healthcare professionals after prostate cancer. European Journal of Cancer Care (Engl), [published online ahead of print]. doi: 10.1111/ ecc.12469. 

Ussher J. M., Perz, J., Rose, D., Dowsett, G. W., Chambers, S., Williams, S., Davis I, Latini, D. (2016). Threat of sexual disqualification: The consequences of erectile dysfunction and other sexual changes for gay and bisexual men with prostate cancer. Archives of Sexual Behaviour DOI 10.1007/s10508-016- 0728-0 [available open access].

Chambers SK, Foley E, Clutton S, McDowall R, Occhipinti S, Berry M, Stockler MR, Lepore SJ, Frydenberg M, Gardiner RA, Davis ID, Smith DP. The role of mindfulness in distress and quality of life for men with advanced prostate cancer. Quality of Life Research 2016; 25(12): 3027–3035.

Lawrence N, Martin A, Toner G, Stockler M, Buizen L, Thomson D, Gebski V, Friedlander M, Yeung A, Wong N, Gurney H, Rosenthal M, Singhal N, Kichenadasse G, Wong S, Lewis C, Vasey P, Grimison P. Long-term outcomes of accelerated BEP (bleomycin, etoposide, cisplatin) for advanced germ cell tumours: updated analysis of an Australian multicentre phase II trial by the Australian and New Zealand Urogenital and Prostate Cancer Trials Group [letter]. Annals of Oncology 2016; 27(12): 2302–2303.

McCombie S, Chang D, Sengupta S, Stockler M, Davis I, Hayne D. Moving toward an evidence and consensus based multicentre enhanced recovery pathway for radical cystectomy: results of an ANZUP survey. BJU International 2016; 117: 98–99.

Roncolato FT, Chatfield M, Houghton B, Toner G, Stockler M, Thomson D, Friedlander M, Gurney H, Rosenthal M, Grimison P. The effect of pulmonary function testing on bleomycin dosing in germ cell tumours. Internal Medicine Journal 2016; 46(8): 893–898


ANZUP Conference Presentations 2016


Toner GC, Whitford HS, Kalinowski P, Grimison PS, Stockler MR, Martin AJ, Davis ID, Olver IN, ANZUP Cancer Trials Group. The impact of chemotherapy on cognition: a longitudinal study in testicular cancer. Genitourinary Cancers Symposium; 7–9 Jan 2016; San Francisco.

Lawrence, N. Long-term outcomes of accelerated BEP (bleomycin, etoposide, cisplatin) for advanced germ cell tumors: updated analysis of an Australian multicenter phase II trial. Oral presentation in session: Best of the Best Research in 2016, Medical Oncology Group of Australia Annual Scientific Meeting 2016, August 3-5, Gold Coast, Australia.

Lawrence, N. Long-term outcomes of accelerated BEP (bleomycin, etoposide, cisplatin) for advanced germ cell tumors: updated analysis of an Australian multicenter phase II trial. ANZUP Annual Scientific Meeting 2016, July 10-12, Brisbane, Australia.

ANZUP ASM 2016 Interviews and ASM 2016 Presentations


All interviews and presentations from the ANZUP ASM are available to ANZUP Members only. Membership is free for professional disciplines and groups involved in researching and treating cancers of the genitourinary system. 

ANZUP Journal Articles 2015


Feletto E, Bang A, Cole-Clark D, Chalasani V, Rasiah K, Smith DP. An examination of prostate cancer trends in Australia, England, Canada and USA: is the Australian death rate too high? World Journal of Urology 2015; 33(11): 1677–1687.

Hayne D, Stockler M, McCombie SP, Chalasani V, Long A, Martin A, Sengupta S, Davis ID. BCG+MMC trial: adding mitomycin C to BCG as adjuvant intravesical therapy for highrisk, non-muscle-invasive bladder cancer: a randomised phase III trial (ANZUP 1301). BMC Cancer 2015; 15(1): 432.
 
Sengupta S, Grimison P, Hayne D, Williams S, Chambers S, de Souza P, Stockler M, McJannett M, Toner G, Davis ID. ANZUP—a new co-operative cancer trials group in genitourinary oncology. BJU International 2015; 115(6): 856-858.

Gillessen S, Omlin A, Attard G, de Bono JS, Efstathiou E, Fizazi K, Halabi S, Nelson PS, Sartor O, Smith MR, Soule HR, Akaza H, Beer TM, Beltran H, Chinnaiyan AM, Daugaard G, Davis ID, De Santis M, Drake CG, Eeles RA, Fanti S, Gleave ME, Heidenreich A, Hussain M, James ND, Lecouvet FE, Logothetis CJ, Mastris K, Nilsson S, Oh WK, Olmos D, Padhani AR, Parker C, Rubin MA, Schalken JA, Scher HI, Sella A, Shore ND, Small EJ, Sternberg CN, Suzuki H, Sweeney CJ, Tannock IF & Tombal B: Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015, Annals of Oncology Advance Access, 28 June, 2015.


ANZUP Conference Presentations 2015


Blinman P, Davis I, Martin A, Troon S, Sengupta S, Hovey E, Coskinas X, Kaplan R, Ritchie A, Meade A, Eisen T, Stockler M. Patients’ preferences for adjuvant sorafenib after resection of intermediate or high risk renal cell carcinoma in the sorce trial: What makes it worthwhile? Medical Oncology Group of Australia Annual Scientific Meeting; 5–7 Aug 2015; Hobart.

Davis ID, Stockler MR, Martin AJ, Marchesin V, Deignan O, McDermott R, Parulekar WR, North SA, Graham B, Long AP, Roncolato FT, Yip S, Hague W, Dazo C, Coskinas X, Sweeney C. Randomised phase 3 trial of enzalutamide in first line androgen deprivation therapy for metastatic prostate cancer: the ANZUP ENZAMET trial (ANZUP 1304). American Society of Clinical Oncology Annual Meeting; 29 May−2 Jun 2015; Chicago.

Lawrence N, Toner G, Martin A, Stockler M, Yeung A, Wong N, Thomson DB, Gebski V, Yip S, King M, Friedlander M, Quinn D, Tan TH, Chan H, Mazhar D, Hanning F, Weickhardt A, Jeffery M, Stevanovic A, Hovey E, Wyld D, Davis ID, Grimison P, and on behalf of ANZUP. P3 BEP (ANZUP 1302): a randomised phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumours. Clinical Oncological Society of Australia 42nd Annual Scientific Meeting; 17–19 Nov 2015; Hobart.

Williams SG, Davis ID, Sweeney C, Stockler MR, Martin AJ, Marchesin V, Deignan O, McDermott R, Long AP, Roncolato FT, Yip S, Hague W, Tu E, Coskinas X, Nguyen PL. Randomised phase 3 trial of enzalutamide in androgen deprivation therapy with radiation therapy for high risk, clinically localised prostate cancer: the ANZUP ENZARAD trial (ANZUP 1303). American Society of Clinical Oncology Annual Meeting; 29 May−2 Jun 2015; Chicago.

Ussher, JM: Sexual wellbeing and quality of life after prostate cancer: A comparison of gay/ bisexual men and heterosexual men, ANZUP Annual Scientific Meeting, 12-14 July 2015; Sydney.

Ussher, JM; Gay and bisexual men’s experiences of sexuality, identity and relationships after prostate cancer: A qualitative analysis, ANZUP Annual Scientific Meeting, 12-14 July 2015; Sydney.

Yip S, Hague W, Price T, Mitchell P, Davis ID; Brand A; Rosenthal M; Simes RJ, Stockler MR: Pursuing Biospecimens Translational Research in Investigator-Initiated Clinical Trials in Oncology, ACTA International Clinical Trials Symposium, 7-10 October 2015; Sydney

Nguyen P, Williams S, Davis I, Stockler M, Niazi T: Randomised phase 3 trial of enzalutamide in androgen deprivation therapy with radiation therapy for high risk, clinically localised, prostate cancer, ANZUP Annual Scientific Meeting, July 2015; Sydney.

Grummet J, Davis I, Martin A, Buchan N, Chalasani V, Frydenberg M, Hayne D, Lalak A, Patel M, Williams A, Woo H, Lawrence N, Chan H, Bishop C, Wong N, Coskinas X, Stockler M: Randomised phase 3 double-blind placebo-controlled trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasound-guided prostate biopsy (Pain-Free TRUS B): ANZUP 1501, Clinical Oncology Society of Australia Annual Scientific Meeting; 17-19 Nov 2015; Hobart.

Davis ID, Stockler MR, Martin A, Marchesin V, Deignan O, McDermott R, Parulekar WR, North SA, Graham B, Chowdhury S, Long AP, Roncolato FT, Yip S, Hague W, Dazo C, Coskinas X, Sweeney C: Randomised phase 3 trial of enzalutamide in first line androgen deprivation therapy for metastatic prostate cancer: the ANZUP ENZAMET Trial (ANZUP 1304). American Society of Clinical Oncology Annual Meeting; 29 May−2 Jun 2015; Chicago.

Williams SG, Davis IDD, Sweeney C, Stockler MR, Martin A, Hague W, Coskinas X, Yip S, Tu E, Chan H, Lawrence N, McDermott R, Hughes S, Marchesin V, Deignan O, Nguyen PL: Randomised phase 3 trial of enzalutamide in androgen deprivation therapy (ADT) with radiation therapy for clinically localised high risk or node-positive, clinically localized, prostate cancer: ENZARAD (ANZUP 1303). American Society of Clinical Oncology Annual Meeting; 29 May−2 Jun 2015; Chicago.

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