Trial Title:

Novel Integration of new prostate radiation therapy schedules with adjuvant androgen deprivation

Trial Acronym:


Protocol Number:

TROG 18.01

Trial Design:

Phase II randomised


TROG Cancer Research

ANZ Study Chairs:

A/Prof Jarad Martin and Dr Mark Sidhom

ANZ Coordinating Centre:

Calvary Mater Newcastle and Liverpool/ Campbelltown Hospitals

Trial Coordinator:

Jo Smart and Tess Vuong

Trial Email:

Recruitment Aim:  

Patient Population:

Prostate cancer


Randomised interventional clinical trial comparing two prostate radiation therapy schedules:
1. Monotherapy (40 Gy in 5 fractions)
2. Virtual HDRB Boost (20 Gy in 2 fractions followed by 36 Gy in 12 fractions)

Primary Outcome:

Rate of Biochemial Clinical Control (BCC)

Secondary Outcomes:

  • Rate of replanning following Knowledge Based Planning feedback to centres
  • Rate of centre conversion to prostate MRI only planning



Sites Recruiting:

  • Calvary Mater Newcastle 
  • Liverpool & Campbelltown Hospitals
  • Illawarra Cancer Centre
  • St George Hospital
  • Westmead Hospital
  • Princess Alexandra Hospital
  • Peter MacCallum Cancer Centre

Further Information:

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